Recombinant iNOS Monoclonal Antibody

SKU: AN301568L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:iNOS

Target Synonym:NOS;HEP-NOS;I-NOS;NOS2A;inducible;Inos;MAC-NOS;Inosl;Nitric oxide synthase;NOS type II;Nos2

Research Areas:

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A267

UNIProt ID:P29477

Accession:

Background:Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in inflammation, enhances the synthesis of proinflammatory mediators such as IL6 and IL8.

Concentration:1 mg/mL

Immunogen:Recombinant human iNOS fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:IHC 1:50-1:100

Calculated MW:

ObservedMW: