Recombinant Human Uteroglobin protein

SKU: CD00701

Size:10 ug

Background:Uteroglobin, a member of the Secretoglobin (SCGBs) superfamily, is a multifunctional protein that can exert anti-inflammatory and anti-tumorigenic effects by binding small hydrophobic molecules such as phospholipids and prostaglandins. It is expressed by Clara cells, the non-ciliated, non-mucous secretory cells predominant in lung bronchioles, and by other epithelia that communicate with the external environment. In addition to sequestering pro-inflammatory mediators and carcinogens, Uteroglobin has been implicated in the inhibition of cell migration and invasion, platelet aggregation, and T cell differentiation. Recombinant Human Uteroglobin is a 15.8 kDa homodimeric protein consisting of two 70 amino acid residues.

Research_area:Others

Purity:> 98 % by SDS-PAGE and HPLC analyses.

Source:Escherichia coli.

Full product name:Recombinant Human Uteroglobin

Biological activity:Fully biologically active when compared to standard. The ED5 as determined by the ability of the immobilized protein to support the adhesion of the A549 human lung carcinoma cells is less than 5. μg/ml, corresponding to a specific activity of > 2 IU/mg.

Synonyms:Uteroglobin, Scgb1a1,CC1, CC16, CCPBP, CCSP, UGB, UP-1, UP1, Human

Endotoxin:Less than 0.1 EU/μg of rHuUteroglobin as determined by LAL method.

Storage:-20ºC

Sequence:EICPSFQRVI ETLLMDTPSS YEAAMELFSP DQDMREAGAQ LKKLVDTLPQ KPRESIIKLM EKIAQSSLCN

uniprot accession:P11684;E9PN95

Molecular weight:Approximately 15.8 kDa, a disulfide-linked homodimeric protein containing two 7 amino acid residues polypeptide.

Formulation:

Reconstitution:Lyophilized from a .2 μm filtered concentrated solution in PBS, pH 7.4.