Recombinant Human TAFA-2 protein

SKU: CD00852

Size:5 ug

Background:TAFA-2 also named FAM19A2, is a chemokine-like protein which is belonged to the FAM19/TAFA family. The family is a newly discovered and distantly related to MIP-1α. It contains 5 members and TAFA proteins are highly expressed in specific brain regions. Like other members of the TAFA family, with the exception of TAFA5, mature TAFA1 contains 10 regularly spaced cysteine residues. Human TAFA2 is 97 % a.a. identical to mouse TAFA2. The biological functions of TAFA family members remain to be determined, but they are postulated to act as brain-specific chemokines or neurokines that take parts in regulators of immune and nervous cells.

Research_area:Immunology

Purity:> 95 % by SDS-PAGE and HPLC analyses.

Source:Escherichia coli.

Full product name:Recombinant Human Chemokine-like protein TAFA-2

Biological activity:Fully biologically active when compared to standard. The biological activity is determined by its ability to enhance neurite outgrowth of E16-E18 rat embryonic cortical neurons. rHuTAFA-2, immobilized at 6-24 μg/mL on a 96 well plate, is able to significantly enhance neurite outgrowth.

Synonyms:TAFA-2,FAM19A2, TAFA-2, Human

Endotoxin:Less than 1 EU/μg of rHuTAFA-2 as determined by LAL method.

Storage:-20ºC

Sequence:ANHHKAHHVK TGTCEVVALH RCCNKNKIEE RSQTVKCSCF PGQVAGTTRA APSCVDASIV EQKWWCHMQP CLEGEECKVL PDRKGWSCSS GNKVKTTRVT H

uniprot accession:Q8N3H

Molecular weight:Approximately 11.2 kDa, a single, non-glycosylated polypeptide chain containing 11 amino acids.

Formulation:

Reconstitution:Lyophilized from a .2 μm filtered concentrated solution in 2 × PBS, pH 7.4.