Recombinant Human SULT1A1 Protein (His Tag)

SKU: PKSH033358

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: SULT1A1

Target Synonym: Aryl sulfotransferase 1;HAST1/HAST2;OK/SW-cl.88;P-PST 1;Phenol Sulfotransferase 1;Phenol-Sulfating Phenol Sulfotransferase 1;ST1A1;ST1A3;STP;STP1;SULT1A1;Sulfotransferase 1A1;Thermostable Phenol Sulfotransferase;Ts-PST

Research Areas: Signal Transduction,Cancer,Metabolism

Conjugation:

Target Species: Human

Expression Host: E.coli

Application:

Fusion tag: N-His

UNIProt ID: P50225

Accession: AAH00923.1

Background: Sulfotransferase 1A1 (SULT1A1) is a cytosolic sulfotransferases that is expressed in the liver; lung; adrenal; brain; platelets; and skin. SULT1A1 is a phenol sulfotransferases with thermostable enzyme activity. SULT1A1 utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines; phenolic drugs and neurotransmitters. It is responsible for the sulfonation and activation of minoxidil. SULT1A1 mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk.

Concentration:

Activity: Not validated for activity

Sequence: Met 1-Leu295

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 10% Trehalose, 50mM Nacl, 0.05% Tween 80, pH7.8.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 35.6 kDa

ObservedMW: 32 kDa