Recombinant Human PRTN3 Protein(His Tag)

SKU: PDMH100183

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:PRTN3

Target Synonym:ACPA;AGP 7;AGP7;AGP7 serine proteinase;Azurophil Granule Protein 7;C ANCA;C ANCA antigen;C-ANCA antigen;CANCA;EC 3.4.21.76;Leukocyte proteinase 3;MBN;MBT;MBT WEGENER AUTOANTIGEN;Myeloblastin;Neutrophil proteinase 4;NP 4;NP-4;NP4;P29;PR 3;PR-3;PR3;Proteinase 3

Research Areas:

Conjugation:

Target Species:Human

Expression Host:stable cell line

Application:

Fusion tag:C-His

UNIProt ID:P24158

Accession:P24158

Background:Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro. By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration. May play a role in neutrophil transendothelial migration, probably when associated with CD177.

Concentration:

Activity:Not validated for activity

Sequence:Met1-Pro256

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 1.0 EU/mg of the protein as determined by the LAL method.

Calculated MW:28 kDa

ObservedMW:35 kDa