Recombinant Human Parathyroid Hormone/PTH Protein (1-84)

SKU: PKSH032854

Size: 50μg

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: PTH

Target Synonym: PTH;PTH1;Parathormone;Parathyrin;Parathyroid Hormone

Research Areas: Signal Transduction;

Conjugation:

Target Species: Human

Expression Host: E.coli

Application:

Fusion tag: None

UNIProt ID: P01270

Accession: P01270

Background: Parathyroid hormone is the most important endocrine regulator of calcium and phosphorus concentration in extracellular fluid. This hormone is secreted from cells of the parathyroid glands and finds its major target cells in bone and kidney. Another hormone; parathyroid hormone-related protein; binds to the same receptor as parathyroid hormone and has major effects on development. Like most other protein hormones; parathyroid hormone is synthesized as a preprohormone. After intracellular processing; the mature hormone is packaged within the Golgi into secretory vesicles; the secreted into blood by exocytosis. Parathyroid hormone is secreted as a linear protein of 84 amino acids.

Concentration:

Activity: Not validated for activity

Sequence: Ser32-Gln115

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of 10mM HAc-NaAc, 150mM NaCl, 5% Mannitol, pH 4.0.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 9.4 kDa

ObservedMW: 14 kDa