Recombinant Human MGAT2/GlcNAc-TII Protein (His Tag)

SKU: PKSH032737

Size: 50μg

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: MGAT2;GlcNAc-TII

Target Synonym: 2-N-acetylglucosaminyltransferase II;6-Mannosyl-Glycoprotein 2-Beta-N-Acetylglucosaminyltransferase;Alpha-1;Beta-1;GlcNAc-T II;MGAT2;Mannoside Acetylglucosaminyltransferase 2;N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase II;NT-II

Research Areas: Tags & Cell Markers

Conjugation:

Target Species: Human

Expression Host: HEK293 Cells

Application:

Fusion tag: C-His

UNIProt ID: Q10469

Accession: Q10469

Background: Mannoside Acetylglucosaminyltransferase 2 (MGAT2) is a single-pass type II membrane protein that contains the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain and a C-terminal catalytic domain. MGAT2 catalyzes an essential step in the conversion of oligo-mannose to complex N-glycans. Defects in MGAT2 are the cause of congenital disorder of glycosylation type 2A.

Concentration:

Activity: Not validated for activity

Sequence: Arg30-Gln447

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 49.3 kDa

ObservedMW: 50 kDa