Recombinant Human MCP-3/CCL7 protein

SKU: CD01314

Size:2 ug

Background:Human CCL7, also known as monocyte chemotactic protein 3 (MCP-3), is belonging to the CC chemokine family. MCP-3 has two homogeneous MCP-1 (CCL2) and MCP-2 (CCL8). These three MCPs were found by IL-1-beta triggered human MG-63 osteosarcoma cells. CCL7 shares 71 % and 58 % a.a. sequence identity with MCP-1 and MCP-2, respectively. CCL7 has chemotactic function for monocytes and eosinophils, but not for neutrophils. In addition, it can also chemoattract activated NK cells.

Research_area:Immunology

Purity:> 97 % by SDS-PAGE and HPLC analyses.

Source:Escherichia coli.

Full product name:Recombinant Human Monocyte Chemotactic Protein-3/CCL7

Biological activity:Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human monocytes is in a concentration range of 1-1 ng/ml.

Synonyms:MCP-3/CCL7, A-152E5.3, ABCD-2, SCYA17, TARC, Human

Endotoxin:Less than 1 EU/μg of rHuMCP-3/CCL7 as determined by LAL method.

Storage:-20ºC

Sequence:QPVGINTSTT CCYRFINKKI PKQRLESYRR TTSSHCPREA VIFKTKLDKE ICADPTQKWV QDFMKHLDKK TQTPKL

uniprot accession:P898

Molecular weight:Approximately 9. kDa, a single, non-glycosylated polypeptide chain containing 76 amino acids.

Formulation:

Reconstitution:Lyophilized from a .2 μm filtered concentrated solution in 2 mM PB, pH 7.4, 15 mM NaCl.