Recombinant Human KIT/SCFR Protein (His Tag)

SKU: PDEH100679

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:KIT;SCFR

Target Synonym:C Kit;CD117;KIT;KIT oncogene;KIT proto oncogene receptor tyrosine kinase;Kit;Kit Ligand;MGF;Mast cell growth factor receptor;Mast/stem cell growth factor receptor Kit;PBT;Piebald trait protein;Proto oncog;Proto oncogene c Kit;c-Kit;c-Kit Ligand;p145 c-kit

Research Areas:Immunology,Tags & Cell Markers,Signal Transduction,Neuroscience,Stem Cells,Cancer,Developmental Biology

Conjugation:

Target Species:Human

Expression Host:E.coli

Application:

Fusion tag:N-His

UNIProt ID:P10721

Accession:P10721-1

Background:This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

Concentration:

Activity:Not validated for activity

Sequence:Gln26-Arg205

Purity: > 95% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from sterile PBS, pH 7.4.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 10 EU/mg of the protein as determined by the LAL method.

Calculated MW:20.1 kDa

ObservedMW:22.4 kDa