Recombinant Human Interleukin-2/IL-2 Protein (C145S)

SKU: PKSH033623

Size: 50μg

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Cytokines

Abbreviation: Interleukin-2;IL-2

Target Synonym: IL2;IL-2;TCGF;lymphokine;IL3;IL4;IL5;IL6;Aldesleukin;IL-2lymphokine;interleukin-2;Proleukin;interleukin 2;involved in regulation of T-cell clonal expansion;T cell growth factor;T-cell growth factor;IL 2;IL2;Interleukin 2;interleukin2;Involved in regulation of T cell clonal expansion;Lymphokine;POIL2;T Cell Growth Factor;TCGF

Research Areas: immunology

Conjugation:

Target Species: Human

Expression Host: E.coli

Application: Cell culture

Fusion tag: None

UNIProt ID: P60568

Accession: P60568

Background: Interleukin-2(IL-2) is an interleukin; a type of cytokine signaling molecule in the immune system;belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells; NK cells; lymphokine-activated killer cells; monocytes; macrophages and oligodendrocytes.

Concentration:

Activity: Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cells. The ED50 for this effect is 90-270 pg/ml

Sequence: Pro22-Thr153(Cys145Ser)

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of 10mM Acetata-Na, 5% Trehaiose, pH 4.5.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 15.5 kDa

ObservedMW: 14 kDa