Recombinant Human IL-20RA/IL-20R1 Protein (His Tag)

SKU: PKSH032576

Size: 50μg

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Cytokines

Abbreviation: IL-20RA;IL-20R1

Target Synonym: UNQ;PRO;Cytokine Receptor Class-II Member;Cytokine Receptor Family 2 Member;CRF2;IL-20R;ZcytoR;CRF2-8;Cytokine Receptor Class-II Member 8;Cytokine Receptor Family 2 Member 8;IL-20 Receptor Subunit Alpha;IL-20R1;IL-20RA;IL-20R-Alpha;Interleukin-20 Receptor Subunit Alpha;ZcytoR7;IL20RA;UNQ681;PRO1315;alpha;class II cytokine receptor ZCYTOR7;CRF2 8;Cytokine receptor class II member 8;I20RA;IL 20R alpha;IL 20R1;Interleukin 20 receptor;Interleukin 20 receptor alpha chain;interleukin-20 receptor I

Research Areas: immunology

Conjugation:

Target Species: Human

Expression Host: HEK293 Cells

Application:

Fusion tag: C-His

UNIProt ID: Q9UHF4

Accession: Q9UHF4

Background: Interleukin-20 Receptor Subunit α (IL20RA) is a single-pass type I membrane protein that is a member of the type II cytokine receptor family. IL20RA is synthetized a 553 amino acid glycoprotein precursor containing a 29 amino acid signal peptide; a 221 amino acid extracellular domain with two fibronectin type-III domains; a 24 amino acid transmembrane region; and a 279 amino acid intracellular domain. IL20RA is widely expressed with highest levels found in skin and testis and high levels in brain. IL20RA forms a heterodimer with IL20RB; and the complex serves as a receptor for IL19; IL20 and IL24. IL20RA also forms a heterodimer with the unique and specific receptor IL10RB and functions as the receptor for IL26.

Concentration:

Activity: Not validated for activity

Sequence: Val30-Lys250

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 26.3 kDa

ObservedMW: 35-50 kDa