Recombinant Human IL-1R8/IL1RAPL1 Protein (Fc Tag)

SKU: PKSH033635

Size: 50μg

Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Exp date: 12 months

Category ID_II: Recombinant Proteins

Category ID_III: Others

Abbreviation: IL-1R8;IL1RAPL1

Target Synonym: IL1R;OPHN;TIGIRR;MRX;IL1RAPL1;IL1R8;IL1RAPL;MRX10;MRX21;MRX34;OPHN4;TIGIRR-2;IL1RAPL-1;IL-1RAPL-1;IL-1-RAPL-1;Interleukin-1 Receptor Accessory Protein-Like 1;Oligophrenin-4;Three Immunoglobulin Domain-Containing IL-1 Receptor-Related 2;X-Linked Interleukin-1 Receptor Accessory Protein-Like 1

Research Areas: Neuroscience

Conjugation:

Target Species: Human

Expression Host: HEK293 Cells

Application:

Fusion tag: C-Fc

UNIProt ID: Q9NZN1

Accession: Q9NZN1

Background: Interleukin-1 receptor accessory protein-like 1; also known as IL1RAPL1; can be detected at low levels in heart; skeletal muscle; ovary; skin; amygdala; caudate nucleus; corpus callosum; hippocampus; substantia nigra and thalamus. IL1RAPL1 functions as a homodimer; it interacts with NCS1; PTPRD. This interaction is PTPRD-splicing-dependent and induces pre- and post-synaptic differentiation of neurons and is required for IL1RAPL1-mediated synapse formation. During dendritic spine formation; it can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD.

Concentration:

Activity: Not validated for activity

Sequence: Leu19-Thr357

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Please refer to the printed manual for detailed information.

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 68.0 kDa

ObservedMW: 80-100 kDa