Recombinant Human GSTAL Protein(Trx Tag)

SKU: PDEH100656

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:GSTAL

Target Synonym:GST;GTH;GSTA;HA subunit;GST HA subunit;GST class alpha member;GST class-alpha member;Glutathione S transferase A;Glutathione S alkyltransferase A;S (hydroxyalkyl)glutathione lyase A;GSTA1;GST-epsilon;GST2;GSTA1-1;GTH1;Glutathione S alkyltransferase A1;GST class-alpha member 1;HA subunit 1;S (hydroxyalkyl)glutathione lyase A1;Glutathione S transferase A1;GST class alpha member 1;GST epsilon;GST HA subunit 1;GSTA1 1;Glutathione S transferase 2;Glutathione S transferase Ha subunit 1;GST class-alpha member 1;GST epsilon;GST HA subunit 1;GST2;GSTA1;GSTA1-1;GST-epsilon;GTH1;HA subunit 1;MGC131939

Research Areas:Signal Transduction;Tags & Cell Markers;Metabolism

Conjugation:

Target Species:Human

Expression Host:E.coli

Application:

Fusion tag:N-Trx

UNIProt ID:P08263

Accession:P08263

Background:GSTA1 (Glutathione S-Transferase Alpha 1) is a Protein Coding gene. This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds. Glutathione S-transferases (GSTs) are involved in the detoxification of carcinogens and may be linked to carcinogenesis. As a vital component of GSTs, GSTA1 plays an important role in carcinogenesis. GSTA1 expression may be a target molecule in the early diagnosis and treatment of lung cancer. Human colonic adenocarcinoma (Caco-2) cells in culture undergo spontaneous differentiation into mature enterocytes in association with progressive increases in expression of glutathione S-transferase alpha-1 (GSTA1). GSTA1 levels may play a role in modulating enterocyte proliferation but do not influence differentiation or apoptosis. GSTA1 may play a key role during pregnancy.

Concentration:

Activity:Not validated for activity

Sequence:Met1-Phe222

Purity:> 95% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis

Endotoxin:< 10 EU/mg of the protein as determined by the LAL method

Calculated MW:44.4 kDa

ObservedMW:39 kDa