Recombinant Human Galectin-3 Protein(His Tag)

SKU: PDEH100578

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:Galectin-3

Target Synonym:MAC;Galactose-specific lectin;Galactoside-Binding Soluble;Galectin;Lectin L;GAL;CBP;LGALS3;CBP35;GAL3;GALBP;GALIG;L31;LGALS2;MAC2;Galactoside-Binding Soluble 3;Lectin;Galectin-3;Gal-3;L-31;35 kDa lectin;CBP 35;Galactose-specific lectin 3;IgE-binding protein;Laminin-binding protein;Lectin L-29;Mac-2 antigen;Carbohydrate binding protein 35;Carbohydrate-binding protein 35;galactose binding;galactoside binding soluble 3;Galactoside-binding protein;galectin 3;Galectin 3 internal gene;Galectin3;GBP;IgE binding protein;included;L 31;L 34;L-34 galactoside-binding lectin;Lectin;Galactoside-Binding Soluble 3;LEG3;MAC 2 antigen;Mac-2;Macrophage galactose-specific lectin;MGC105387;P35;soluble 3

Research Areas:Neuroscience;Cell Biology

Conjugation:

Target Species:Human

Expression Host:E.coli

Application:

Fusion tag:N-His

UNIProt ID:P17931

Accession:P17931

Background:Galectin-3 (Galectin 3) is a Protein Coding gene. This gene encodes a member of the galectin family of carbohydrate-binding proteins. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. Galectin-3 is a beta-galactoside-binding lectin and plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion, and T-cell regulation. Galectin-3 has an important role in tumor progression throμgh inhibition of apoptosis. Galectin-3 expression is associated with neoplastic transformation and with differentiation of monocytes to macrophages. Elevated expression of Galectin-3 has been demonstrated in the synovium of rheumatoid arthritis (RA). Diseases associated with Galectin-3 include Follicular Adenoma and Papillary Carcinoma.

Concentration:

Activity:Not validated for activity

Sequence:2Ala-250Iie

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 10 EU/mg of the protein as determined by the LAL method.

Calculated MW:27.4 kDa

ObservedMW:32 kDa