Recombinant Human CXCL3/CINC-2α/β Protein(Trx Tag)

SKU: PDEH100600

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:CXCL3/CINC-2α/β

Target Synonym:GRO;CXCL;SCYB;C-X-C Motif Chemokine;CINC-2b;C-X-C Motif Chemokine 3;GRO-Gamma;GRO-Gamma (1-73);GRO-Gamma (5-73);Growth-Regulated Protein Gamma;Macrophage Inflammatory Protein 2-Beta;MIP2B;MIP-2b;MIP2-Beta;CXCL3;GRO3;GROG;SCYB3

Research Areas:Immunology

Conjugation:

Target Species:Human

Expression Host:E.coli

Application:

Fusion tag:N-Trx

UNIProt ID:P19876

Accession:P19876

Background:CXCL3/CINC-2α/β is involved in migration, invasion, proliferation and tubule formation of trophoblasts and may play a key role in the pathogenesis of preeclampsia. CXCL3/CINC-2α/β autocrine/paracrine pathways are involved in the development of prostate cancer by regulating the expression of the target genes that are related to the progression of malignancies. CXCL3/CINC-2α/β is a novel adipokine that facilitates adipogenesis in an autocrine and/or a paracrine manner throμgh induction of c/ebpb and c/ebpd. CXCL3/CINC-2α/β and its receptor CXCR2 are overexpressed in prostate cancer cells, prostate epithelial cells and prostate cancer tissues, which may play multiple roles in prostate cancer progression and metastasis.

Concentration:

Activity:Not validated for activity

Sequence:Cys35-Phe107

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 10 EU/mg of the protein as determined by the LAL method.

Calculated MW:27.9 kDa

ObservedMW:30 kDa