GeneBio Systems
Recombinant Human CCL8/MCP-2 Protein (Human Cells, His Tag)
Recombinant Human CCL8/MCP-2 Protein (Human Cells, His Tag)
SKU:PKSH032202
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Size: 50μg
Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Exp date: 12 months
Category ID_II: Recombinant Proteins
Category ID_III: Cytokines
Abbreviation: CCL8;MCP-2
Target Synonym: C-C Motif Chemokine 8;CCL8;HC14;MCP-2;MCP2;Monocyte Chemoattractant Protein 2;Monocyte Chemotactic Protein 2;SCYA10;SCYA8;Small-Inducible Cytokine A8
Research Areas: immunology
Conjugation:
Target Species: Human
Expression Host: HEK293 Cells
Application:
Fusion tag: C-His
UNIProt ID: P80075
Accession: AAI26243.1
Background: Human Chemokine (C-C Motif) Ligand 8 (CCL8) is produced by human MG63 osteosarcoma cells. CCL8 shares 62% and 58% amino acid sequence identity with MCP-1 and MCP-3; respectively. All three MCP proteins are monocyte chemoattractants. CCL8 is chemotactic for and activates many different immune cells; including mast cells; eosinophils and basophils; which are implicated in allergic response; and monocytes; T cells; and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors including CCR1; CCR2B and CCR5.
Concentration:
Activity: Not validated for activity
Sequence: Gln24-Pro99
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM EDTA, pH 7.4.
Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Reconstitution: Please refer to the printed manual for detailed information.
Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Calculated MW: 10.0 kDa
ObservedMW: 13 kDa
