Recombinant HDAC4 Monoclonal Antibody

SKU: AN300809L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:HDAC4

Target Synonym:AHO;KIAA;EC 3.5.1.;Histone deacetylase;HDAC4;AHO3;BDMR;HA6116;HD4;HDAC-4;HDAC-A;HDACA;EC 3.5.1.98;HD 4;HDAC 4;HDAC A;Histone deacetylase 4;Histone Deacetylase A;KIAA0288

Research Areas:Stem Cells;Epigenetics and Nuclear Signaling;Cardiovascular;Neuroscience

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:4B8

UNIProt ID:P56524

Accession:

Background:Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human HDAC4 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000

Calculated MW:119 kDa

ObservedMW:140 kDa