Recombinant GOT2 Monoclonal Antibody

SKU: AN301538L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:GOT2

Target Synonym:KAT;GOT;KYAT;GOT2;KAT4;KATIV;KYAT4;mitAAT;AATM;AL022787;Aspartate aminotransferase;Aspartate aminotransferase 2;Aspartate transaminase 2;ASPATA;EC 2.6.1.1;FABP 1;FABP pm;FABP-1;FABPpm;Fatty acid binding protein;Fatty acid-binding protein;FLJ40994;Glutamate oxaloacetate transaminase;Glutamate oxaloacetate transaminase 2;Glutamic oxaloacetic transaminase 2;Got 2;kynurenine aminotransferase 4;Kynurenine aminotransferase IV;kynurenine--oxoglutarate transaminase 4;kynurenine--oxoglutarate transaminase IV;mAspAT;MGC102129;MGC115763;mitochondrial;mitochondrial (aspartate aminotransferase 2);Mitochondrial aspartate aminotransferase;OTTMUSP00000017748;Plasma membrane fatty acid binding protein;Plasma membrane-associated fatty acid-binding protein;Transaminase A

Research Areas:Signal Transduction;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A237

UNIProt ID:P00505

Accession:

Background:Aspartate aminotransferase, mitochondrial is an enzyme that in humans is encoded by the GOT2 gene. Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. Also, GOT2 is a major participant in the malate-aspartate shuttle, which is a passage from the cytosol to the mitochondria. The two enzymes are homodimeric and show close homology. GOT2 has been seen to have a role in cell proliferation, especially in terms of tumor growth.

Concentration:1 mg/mL

Immunogen:Recombinant human GOT2 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:1000;IHC 1:50-1:100

Calculated MW:42 kDa

ObservedMW:42 kDa