Recombinant GOLGA2/GM130 Monoclonal Antibody

SKU: AN302050L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:GOLGA2/GM130

Target Synonym:GOLGA;golgin A;GOLGA2;GM130;golgin A2;130 kDa cis Golgi matrix protein;130 kDa cis-Golgi matrix protein;Cis golgi matrix protein GM130;Gm130 autoantigen;GOGA2;GOLGA 2;Golgi autoantigen;Golgi autoantigen golgin subfamily a 2;Golgi matrix protein GM130;Golgin 95;Golgin subfamily a 2;Golgin subfamily A member 2;Golgin-95;MGC20672;SY11 protein

Research Areas:Tags & Cell Markers;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A770

UNIProt ID:Q08379

Accession:

Background:Peripheral membrane component of the cis-Golgi stack that acts as a membrane skeleton that maintains the structure of the Golgi apparatus,and as a vesicle thether that facilitates vesicle fusion to the Golgi membrane. Required for normal protein transport from the endoplasmicreticulum to the Golgi apparatus and the cell membrane. Together with p115/USO1 and STX5, involved in vesicle tethering and fusion at thecis-Golgi membrane to maintain the stacked and inter-connected structure of the Golgi apparatus. Plays a central role in mitotic Golgidisassembly: phosphorylation at Ser-37 by CDK1 at the onset of mitosis inhibits the interaction with p115/USO1, preventing tethering of COPIvesicles and thereby inhibiting transport through the Golgi apparatus during mitosis. Also plays a key role in spindle pole assembly andcentrosome organization.

Concentration:1 mg/mL

Immunogen:Peptide. This information is proprietary to PTMab.

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:1000;IHC 1:50-1:100

Calculated MW:113 kDa

ObservedMW:130 kDa