Recombinant Filamin A Monoclonal Antibody

SKU: AN300953L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:Filamin A

Target Synonym:ABP;CVD;FLNA;ABP-280;ABPX;CSBS;CVD1;FLN;FLN-A;FLN1;FMD;MNS;NHBP;OPD;OPD1;OPD2;XLVD;XMVD;filamin-A;ABP 280;Actin-binding protein 280;Alpha filamin;Alpha-filamin;APBX;Endothelial actin binding protein;Endothelial actin-binding protein;FGS2;Filamin 1;filamin A;Filamin A alpha;Filamin-1;Non muscle filamin;Non-muscle filamin;Filamin 1

Research Areas:Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:4F12

UNIProt ID:P21333

Accession:

Background:FLNA(filamin A) Homo sapiens The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human Filamin A protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:1000-1:5000

Calculated MW:281 kDa

ObservedMW:281 kDa