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GeneBio Systems

Recombinant FDPS/Farnesyl Diphosphate Synthase Monoclonal Antibody

Recombinant FDPS/Farnesyl Diphosphate Synthase Monoclonal Antibody

AN300076P

£182.00 GBP
£182.00 GBP
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Size::20μL

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:FDPS

Target Synonym:KIAA;POROK;FDPS;FPPS;FPS;POROK9;Dimethylallyltranstransferase;Farnesyl diphosphate synthase;Farnesyl diphosphate synthetase;Farnesyl pyrophosphate synthase;Farnesyl pyrophosphate synthetase;FPP synthase;FPP synthetase;FPPS_HUMAN;Geranyltranstransferase;KIAA1293

Research Areas:Cardiovascular;Signal Transduction;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB;FCM;ICC/IF;IP

Isotype:IgG

Clonality:Rabbit Monoclonal

Clone NO.:11D13

UNIProt ID:P14324

Accession:

Background:This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 18 and X. Multiple transcript variants encoding different isoforms have been found for this gene.

Concentration:1 mg/mL

Immunogen:Recombinant Human FDPS / Farnesyl Diphosphate Synthase protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:WB 1:500-1:2000;FCM 1:25-1:100;ICC/IF 1:20-1:100;IP 1-4 μL/mg of lysate

Calculated MW:48 kDa

ObservedMW:38 kDa

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