Recombinant DNMT3B Monoclonal Antibody

SKU: AN302070L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:DNMT3B

Target Synonym:DNMT3B;ICF;ICF1;M.HsaIIIB;DNA MTase HsaⅢB|DNA cytosine-5 methyltransferase 3 beta|DNA methyltransferase HsaⅢB;M.HsaⅢB

Research Areas:Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:WB;ChIP

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A790

UNIProt ID:Q9UBC3

Accession:

Background:The DNMT3 family consists of two active methyltransferases, DNMT3A and DNMT3B, along with a DNMT3-like protein known as DNMT3L.DNMT3B plays a crucial role in regulating specific DNA methylation patterns, particularly during de novo methylation. It may function as atranscriptional corepressor by associating with CBX4 independently of DNA methylation. Mutations in the DNMT3B gene lead toImmunodeficiency-centromeric instability-facial anomalies (ICF) syndrome.

Concentration:1 mg/mL

Immunogen:Peptide. This information is proprietary to PTMab.

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:1000-1:2000;ChIP 6 μg/2×10⁶ cells

Calculated MW:96 kDa

ObservedMW:96 kDa