Recombinant DNMT1 Monoclonal Antibody

SKU: AN301728L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:DNMT1

Target Synonym:MGC;CXXC;DNA methyltransferase;CXXC finger protein 9|DNA methyltransferase;ADCADN;AIM;CXXC9;DNMT;HSN1E;MCMT;m.HsaI;DNMT1;CXXC finger protein 9|DNA methyltransferase 1;DNA methyltransferase 1;FLJ16293;MGC104992;ADCADN;AIM;CXXC9;DNA methyltransferase 1;DNMT;HSN1E;m.HsaI;MCMT;CXXC finger protein 9;CXXC-type zinc finger protein 9;DNA (cytosine 5 ) methyltransferase 1;DNA (cytosine-5)-methyltransferase 1;DNA methyltransferase HsaI;DNA methyltransferase M.HsaI.;DNA MTase;DNA MTase HsaI;DNMT 1;Dnmt1o;Met1;mMmul;MommeD2

Research Areas:Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:WB;IHC;IF;IP

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A436

UNIProt ID:P26358

Accession:

Background:Dnmt1 is an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities.

Concentration:1 mg/mL

Immunogen:Recombinant human Dnmt1 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:1000;IHC 1:200-1:1000;IF 1:50;IP 1:25-1:50

Calculated MW:183 kDa

ObservedMW:200 kDa