Recombinant DLL3 Monoclonal Antibody

SKU: AN301506L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:DLL3

Target Synonym:Dll;DLL3

Research Areas:Neuroscience;Cell Biology;Epigenetics and Nuclear Signaling;Developmental Biology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A205

UNIProt ID:Q9NYJ7

Accession:

Background:Delta-like protein 3 (DLL3), as a ligand of the Notch pathway, is specifically and highly expressed on the surface of SCLC (small cell lung cancer) cells. It plays an important role in tumor initiation, epithelial-mesenchymal transition, invasion and metastasis of SCLC. Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm.

Concentration:1 mg/mL

Immunogen:Recombinant human DLL3 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:1000

Calculated MW:65 kDa

ObservedMW:65 kDa