Recombinant CX3CR1 Monoclonal Antibody

SKU: AN301864L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:CX3CR1

Target Synonym:GPR;CCRL;GPRV;CX3CR;CMKDR;CMKBRL;CX3CR1;CCRL1;CMKBRL1;CMKDR1;GPR13;GPRV28;V28;Beta chemokine receptor-like 1;CMK-BRL1;CMK-BRL-1;CX3C chemokine receptor 1;C-X3-C CKR-1;C-X3-C motif chemokine receptor 1;fractalkine receptor;G-protein coupled receptor 13

Research Areas:Microbiology;Tags & Cell Markers;Immunology;Neuroscience;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A576

UNIProt ID:P49238

Accession:

Background:CX3CR1 is a G-protein-coupled seven-transmembrane chemokine receptor, also known as GPR13 or V28. It is expressed on microglia, astrocytes, NK cells, monocytes/macrophages, and a subpopulation of T cells. CX3CR1 is the receptor for fractalkine (CX3CL1) and mediates both its adhesive and migratory functions. It also acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro), and some variations in the gene of CX3CR1 lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Defects in CX3CR1 are a cause of susceptibility to age-related macular degeneration type 12 (ARMD12).

Concentration:1 mg/mL

Immunogen:Recombinant human CX3CR1 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:1000

Calculated MW:40 kDa

ObservedMW:50 kDa