Recombinant Complement C4-B Monoclonal Antibody

SKU: AN301451L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:Complement C4-B

Target Synonym:CPAMD;Basic C;Basic C4;C4(Chido Blood Group);C4-B;C4B;C4B_2;CO4;CPAMD3

Research Areas:Immunology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A146

UNIProt ID:P0C0L5

Accession:

Background:Non-enzymatic component of the C3 and C5 convertases and thus essential for the propagation of the classical complement pathway. Covalently binds to immunoglobulins and immune complexes and enhances the solubilization of immune aggregates and the clearance of IC through CR1 on erythrocytes. C4A isotype is responsible for effective binding to form amide bonds with immune aggregates or protein antigens, while C4B isotype catalyzes the transacylation of the thioester carbonyl group to form ester bonds with carbohydrate antigens.

Concentration:1 mg/mL

Immunogen:Recombinant human Complement C4-B fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:2000;IHC 1:200-1:1000

Calculated MW:193 kDa

ObservedMW:193, 85 kDa