Recombinant Cleaved PARP1 p85 Monoclonal Antibody

SKU: AN301495L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:Cleaved PARP1 p85

Target Synonym:SCA;ARTD;Poly[ADP-ribose] synthase;Poly ADP ribose polymerase;poly(ADP-ribose) polymerase;Poly [ADP-ribose] polymerase;NAD(+) ADP-ribosyltransferase;ADP-ribosyltransferase diphtheria toxin-like;pADPRT;ADPRT;ADPRT 1;ADPRT1;ARTD1;PARP;PARP-1;PPOL;pADPRT-1;PARP1;Cleaved PARP;ADP-ribosyltransferase diphtheria toxin-like 1;APOPAIN;NAD(+) ADP-ribosyltransferase 1;Poly [ADP-ribose] polymerase 1;Poly ADP ribose polymerase 1;poly(ADP-ribose) polymerase 1;Poly[ADP-ribose] synthase 1;SCA1;ADPRT;ADPRT 1;ADPRT1;ARTD1;pADPRT-1;PARP;PARP-1;poly(ADP-ribose) polymerase 1;PPOL

Research Areas:Cell Biology;Epigenetics and Nuclear Signaling;Metabolism;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB;IF;FCM;IP

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A190

UNIProt ID:P09874

Accession:

Background:Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair. Mediates glutamate, aspartate, serine or tyrosine ADP-ribosylation of proteins: the ADP-D-ribosyl group of NAD+ is transferred to the acceptor carboxyl group of target residues and further ADP-ribosyl groups are transferred to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units.Serine ADP-ribosylation of proteins constitutes the primary form of ADP-ribosylation of proteins in response to DNA damage.

Concentration:1 mg/mL

Immunogen:Recombinant human Cleaved PARP1 p85 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:2000;IF 1:100-1:200;FCM 1:50-1:100;IP 1:50

Calculated MW:85kDa

ObservedMW:89kDa