Recombinant Claudin 18.2 Monoclonal Antibody

SKU: AN301831L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:Claudin 18.2

Target Synonym:UNQ;PRO;CLDN;SFTA;Claudin;Claudin-;CLDN18;SFTA5;SFTPJ;Claudin-18;Claudin-18.2;UNQ778;PRO1572;SPJ

Research Areas:Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A543

UNIProt ID:P56856

Accession:

Background:Claudin 18 (CLDN18) belongs to the large claudin family of proteins, which are tetraspan transmembrane proteins of tight junctions. Claudins exhibit specific patterns of expression in different tissues. CLDN18 is specifically expressed in the stomach and lung. CLDN18 has two alternatively spliced variants, CLDN18.1 and CLDN18.2. CLDN18.2 is a highly selective gastric lineage marker that determines the gastric phenotype in a neoplastic condition, whereas CLDN18.1 is lung specific. Altered CLDN18 expression has been reported in various human malignancies, including gastric cancer, lung adenocarcinoma, and pancreatic neoplasm.

Concentration:1 mg/mL

Immunogen:Recombinant human Claudin 18.2 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:IHC 1∶200-1∶1000

Calculated MW:

ObservedMW: