Recombinant CHOP Monoclonal Antibody

SKU: AN300931L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:CHOP

Target Synonym:DDIT;GADD;DNA damage inducible transcript;DDIT3;CEBPZ;CHOP;CHOP-10;CHOP10;GADD153;C/EBPzeta;DDIT3 / CHOP;DNA damage inducible transcript 3;CEBPZ;CHOP;CHOP10;CHOP-10;DNA damage inducible transcript 3;GADD153;C/EBP homologous protein;C/EBP Homology Protein;C/EBP zeta;C/EBP-homologous protein;C/EBP-homologous protein 10;CCAAT/enhancer binding protein homologous protein;CHOP 10;DDIT 3;DDIT-3;DNA damage-inducible transcript 3 protein;GADD 153;Growth Arrest and DNA Damage Inducible Protein 153;Growth arrest and DNA damage inducible protein GADD153;Growth arrest and DNA damage-inducible protein GADD153;MGC4154

Research Areas:Epigenetics and Nuclear Signaling;Stem Cells;Developmental Biology;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:7A2

UNIProt ID:P35638

Accession:

Background:This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human CHOP protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:1000-1:4000;WB 1:1000-1:5000

Calculated MW:19 kDa

ObservedMW:30 kDa