Recombinant CDK1/Cdc2 Monoclonal Antibody

SKU: AN301969L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:CDK1/Cdc2

Target Synonym:CDC;CDK;CDKN;cyclin-dependent kinase;P34CDC;CDK1;CDC2;CDC28A;P34CDC2;cyclin-dependent kinase 1;CDKN1;CDC2;CDC28A;cyclin-dependent kinase 1;P34CDC2;cyclin dependent kinase 1874

Research Areas:Cell Biology;Epigenetics and Nuclear Signaling;Cancer;Neuroscience;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse;African green monkey

Application:WB;IHC;IF;FCM

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A685

UNIProt ID:P06493

Accession:

Background:CDC2, also named as CDK1, belongs to the protein kinase superfamily. The entry of eukaryotic cells into mitosis is regulated by cdc2 kinase activation, a process controlled at several steps including cyclin binding and phosphorylation of cdc2 at Thr161. However, the critical regulatory step in activating cdc2 during progression into mitosis appears to be dephosphorylation of cdc2 at Thr14 and Tyr15. Phosphorylation at Thr14 and Tyr15, resulting in inhibition of cdc2, can be carried out by Wee1 and Myt1 protein kinases.

Concentration:1 mg/mL

Immunogen:Recombinant human CDK1/Cdc2 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:1000;IHC 1:50-1:100;IF 1:50-1:100;FCM 1:50-1:100

Calculated MW:34 kDa

ObservedMW:34 kDa