Recombinant CD8B/P37/LEU2 Monoclonal Antibody

SKU: AN300216P

Size::20μL

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:CD8B

Target Synonym:LYT;LEU;CD8B;CD8B1;LEU2;LY3;LYT3;P37;T-Cell Surface Glycoprotein CD8 Beta Chain;CD8;Lyt3

Research Areas:Immunology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:IHC-P

Isotype:IgG

Clonality:Rabbit Monoclonal

Clone NO.:9A10

UNIProt ID:P10966

Accession:

Background:The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 1, has been identified.

Concentration:1 mg/mL

Immunogen:Recombinant Human CD8B / P37 / LEU2 Protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:IHC-P 1:100-1:500;

Calculated MW:

ObservedMW: