Recombinant CD105 Monoclonal Antibody

SKU: AN301090L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:CD105

Target Synonym:HHT;RP11 228B;Osler Rendu Weber syndrome;END;HHT1;ORW1;CD105;ENG;endoglin;AI528660;AI662476;CD 105;CD105 antigen;EGLN;FLJ41744;ORW;Osler Rendu Weber syndrome 1;RP11 228B15.2;S-endoglin;SN6;AI528660;AI662476;CD 105;CD105;CD105 antigen;EGLN;END;Endoglin;Eng;FLJ41744;HHT1;ORW;ORW1;Osler Rendu Weber syndrome 1;RP11 228B15.2;S-endoglin;SN6;ENG;END;CD105(Endoglin)

Research Areas:Immunology;Stem Cells;Cancer;Cardiovascular

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:6G14

UNIProt ID:P17813

Accession:

Background:This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human CD105 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:100-200;WB 1:1000-5000

Calculated MW:70 kDa

ObservedMW:95 kDa