Recombinant Caspase-7 Monoclonal Antibody

SKU: AN301874L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:Caspase-7

Target Synonym:Mch;Lice;CASP;Lice2;Mch3;Casp7;CASP-7;Caspase 7;CMH-1;ICE-LAP3

Research Areas:

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Rat;Mouse

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A586

UNIProt ID:P97864

Accession:

Background:Caspase-7, also named as CMH-1, Mch3 and ICE-LAP3, has been identified as a major contributor to the execution of apoptosis. Caspase-7, like caspase-3, is an effector caspase that is responsible for cleaving downstream substrates such as ADP-ribose polymerase and PARP. During apoptosis, caspase-7 is activated through proteolytic processing by upstream caspases at Asp23, Asp198, and Asp206 to produce the mature subunits. Similar to caspase-2 and -3, caspase-7 preferentially cleaves substrates following the recognition sequence DEVD.

Concentration:1 mg/mL

Immunogen:Recombinant human Caspase-7 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:1000;IHC 1:200-1:1000

Calculated MW:34 kDa

ObservedMW:34 kDa