Recombinant Carbonic Anhydrase VIII/CA8 Monoclonal Antibody

SKU: AN300188P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:CA8

Target Synonym:CAMRQ;CAMRQ3;Carbonic Anhydrase VIII;Carbonic Anhydrase-Related Protein;CARP;CA-VIII;MGC120502;MGC99509;CALS;CA8

Research Areas:Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB;IP

Isotype:IgG

Clonality:Rabbit Monoclonal

Clone NO.:5C9

UNIProt ID:P35219

Accession:

Background:The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. Carbonic anhydrase protein (CA) VIII, which is a member of the CA gene family, has been shown to have no catalytic CA activity and its biological function is still unknown. Increased expression of CA-RP VIII was observed in 78% of colorectal carcinomas. It suggested that CA-RP VIII plays a role in the process of invasion in colorectal cancer.

Concentration:1 mg/mL

Immunogen:Recombinant Human Carbonic Anhydrase VIII / CA8 protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:WB 1:500-1:1000;IP 0.2-1 μL/mg of lysate

Calculated MW:37 kDa

ObservedMW:37 kDa