Recombinant c-Jun Monoclonal Antibody

SKU: AN300887L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:c-JUN

Target Synonym:AP-1;AP1;c-Jun;JUN;c;Activator protein 1;AP 1;AP-1 transcription factor subunit;cJun;Enhancer Binding Protein AP1;Jun Activation Domain Binding Protein;Jun oncogene;JUN protein;Jun proto oncogene;Jun proto-oncogene;JUNC;Oncogene JUN;p39;Proto oncogene c jun;Proto oncogene cJun;Proto-oncogene c-jun;Transcription Factor AP 1;Transcription Factor AP1;Transcription factor AP-1;V jun avian sarcoma virus 17 oncogene homolog;V jun sarcoma virus 17 oncogene homolog;V jun sarcoma virus 17 oncogene homolog (avian);vJun Avian Sarcoma Virus 17 Oncogene Homolog;V-jun avian sarcoma virus 17 oncogene homolog

Research Areas:Epigenetics and Nuclear Signaling;Signal Transduction;Cancer;Immunology;Kits;Lysates;Other;Cardiovascular

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:5C10

UNIProt ID:P05412

Accession:

Background:Transcription factor that recognizes and binds toThe enhancer heptamer motif 5'-TGA[CG]TCA-3'.,PTM:Phosphorylation enhancesThe transcriptional activity. Phosphorylated by PRKDC.,similarity:Belongs toThe bZIP family.,similarity:Belongs toThe bZIP family. Jun subfamily.,similarity:Contains 1 bZIP domain.,subunit:Heterodimer with either FOS or BATF3. Interacts with HIVEP3 (By similarity). Interacts with SMAD3/SMAD4 heterodimers. Interacts with MYBBP1A, SPIB and TCF20. Interacts with COPS5; indirectly leading to its phosphorylation. Interacts with DSIPI; this interaction inhibitsThe binding of active AP1 to its target DNA.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human c-Jun protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:200-1:1000;WB 1:2000-1:10000

Calculated MW:36 kDa

ObservedMW:43 kDa