Recombinant BRG1 Monoclonal Antibody

SKU: AN300890L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:BRG1

Target Synonym:BRG;SNF;CSS;BAF;MRD;SWI;RTPS;SNF2L;SMARCA;BAF190;BAF190A;BRG1;CSS4;MRD16;RTPS2;SNF2;SNF2L4;SNF2LB;SWI2;hSNF2b;SMARCA4;SNF2B;actin dependent regulator of chromatin;ATP dependent helicase SMARCA4;ATP-dependent helicase SMARCA4;BAF 190;Brahma protein like 1;BRG1 associated factor 190A;BRG1 protein;BRG1-associated factor 190A;BRM/SWI2 related gene 1;Global transcription activator homologous sequence;global transcription activator snf2l4;Homeotic gene regulator;matrix associated;member 4;Mitotic growth and transcription activator;Nuclear protein GRB1;Protein brahma homolog 1;Protein BRG1;Protein BRG-1;SMARC A4;SMCA4;SNF2 beta;SNF2 like 4;SNF2-beta;subfamily a;Sucrose nonfermenting like 4;SWI/SNF related;SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 4;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4;Transcription activator BRG1

Research Areas:Neuroscience;Epigenetics and Nuclear Signaling;Stem Cells;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:7C2

UNIProt ID:P51532

Accession:

Background:The protein encoded by this gene is a member ofThe SWI/SNF family of proteins and is similar toThe brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by alteringThe chromatin structure around those genes.The encoded protein is part ofThe large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulateThe expression ofThe tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human BRG1 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:200-1:1000;WB 1:2000-1:10000

Calculated MW:185 kDa

ObservedMW:220 kDa