Recombinant beta-Catenin/CTNNB1 Monoclonal Antibody

SKU: AN300396P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:CTNNB1

Target Synonym:MRD;PRO;Catenin beta;SW-cl;OK/SW-cl;CTNNB;MRD19;armadillo;beta Catenin;CTNNB1;Beta-catenin;Catenin beta-1;OK;SW-cl.35;OK/SW-cl.35;PRO2286;88kDa;beta 1;Cadherin associated protein;Catenin (cadherin associated protein);Catenin beta 1;CATNB;CHBCAT;CTNB1;DKFZp686D02253;FLJ25606;FLJ37923;OTTHUMP00000162082;OTTHUMP00000165222;OTTHUMP00000165223;OTTHUMP00000209288;OTTHUMP00000209289

Research Areas:Signal Transduction;Neuroscience;Stem Cells;Cancer;Cardiovascular

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:IHC-P;IF;FCM

Isotype:IgG

Clonality:Monoclonal

Clone NO.:9D1

UNIProt ID:P35222

Accession:

Background:The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.

Concentration:1 mg/mL

Immunogen:Recombinant Human beta-Catenin/CTNNB1 protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:IHC-P 1:100-1:500;ICC/IF :1:20-1:100;FCM 1:25-1:100

Calculated MW:

ObservedMW: