Recombinant BDNF Monoclonal Antibody

SKU: AN300600L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:BDNF

Target Synonym:MGC;ANON;BULN;BDNF;ANON2;BULN2;Abrineurin;Brain Derived Neurotrophic Factor;Brain-derived neurotrophic factor;MGC34632;Neurotrophin;ProBDNF

Research Areas:Neuroscience;Cardiovascular;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:2B8

UNIProt ID:P23560

Accession:

Background:The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene. During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human BDNF protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000

Calculated MW:28 kDa

ObservedMW:Precursor 28 kDa, Mature 12-14 kDa