Recombinant Bcr Monoclonal Antibody

SKU: AN301879L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:Bcr

Target Synonym:Renal carcinoma antigen NY-REN;BCR;ALL;BCR1;CML;D22S11;D22S662;PHL;Breakpoint cluster region;Renal carcinoma antigen NY-REN-26;bcr;BCR1;Breakpoint cluster region;CML;D22S11;D22S662;PHL;Renal carcinoma antigen NY-REN-26

Research Areas:Signal Transduction;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A591

UNIProt ID:P11274

Accession:

Background:Break point cluster region protein (Bcr) is encoded by the Bcr gene. The Bcr gene, mapping on chromosome22, was orginally identified by its presence in the chimeric Bcr-Abl oncogene. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine / threonine kinase activity and is a GTPase-activating protein for RAC1 and CDC42. A chromosomal aberration involving BCR has been found in patients with chronic myeloid leukemia.

Concentration:1 mg/mL

Immunogen:Recombinant human Bcr fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:1000;IHC 1:50

Calculated MW:160 kDa

ObservedMW:160 kDa