Recombinant Bag3 Monoclonal Antibody

SKU: AN300926L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:Bag3

Target Synonym:MFM;CAIR;Bcl-2-associated athanogene;BAG family molecular chaperone regulator;BAG;BAG3;BAG-3;BIS;CAIR-1;MFM6;BAG family molecular chaperone regulator 3;Bcl-2-associated athanogene 3;Bcl-2-binding protein Bis;Bcl-2-associated athanogene 3;Bcl-2-binding protein Bis;BIS;BAG 3;BAG family molecular chaperone regulator 3;Bcl 2 binding protein;BCL2 associated athanogene 3;BCL2 binding athanogene 3;CAIR 1;Docking protein CAIR 1;Docking protein CAIR-1;Bag-3

Research Areas:Cell Biology;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:8A1

UNIProt ID:O95817

Accession:

Background:BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human Bag3 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:1000-1:5000

Calculated MW:62 kDa

ObservedMW:80 kDa