Recombinant 4E-BP1 Monoclonal Antibody

SKU: AN300817L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:4E-BP1

Target Synonym:4EBP;eIF4E binding protein;eukaryotic translation initiation factor 4E-binding protein;4E-BP;EIF4EBP;EIF4EBP1;4E-BP1;4EBP1;BP-1;PHAS-I;eukaryotic translation initiation factor 4E-binding protein 1;BP 1;eIF4E binding protein 1;eIF4E-binding protein 1;PHASI;Phosphorylated heat- and acid-stable protein regulated by insulin 1;4EBP1;4E-BP1;BP-1;eukaryotic translation initiation factor 4E-binding protein 1;PHAS-I

Research Areas:Epigenetics and Nuclear Signaling;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:4B16

UNIProt ID:Q13541

Accession:

Background:This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human 4E-BP1 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000

Calculated MW:13 kDa

ObservedMW:17 kDa