RCC1 antibody , Cat. # FNab07208

SKU: FNab07208

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:CHC1, also named as RCC1, promotes the exchange of ran-bound gdp by gtp. It is involved in the regulation of onset of chromosome condensation in the S-phase. Phosphorylation of RCC1 on serines located in or near its nuclear localization signal activates RCC1 to generate RanGTP on mitotic chromosomes, which is required for spindle assembly and chromosome segregation. This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human RCC1.

Immunogen:regulator of chromosome condensation 1

Synonyms:Cell cycle regulatory protein, CHC1, RCC1, RCC1 I

Observed MW:50 kDa

Uniprot ID:P18754

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC, IP, IF

Recommended dilution:WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:20-1:200

Gene ID:1104

Research Area:Cancer, Cell Division and Proliferation, Metabolism