Rat Solute Carrier Family 22 Member 2, SLC22A2 ELISA Kit

SKU: E2335Ra

Size:96 Tests-1 Kit

Background:Mediates tubular uptake of organic compounds from circulation. Mediates the influx of agmatine, serotonin, choline, ranitidine, histamine, creatinine, amantadine, memantine, acriflavine, 4-[4-(dimethylamino)-styryl]-N-methylpyridinium ASP and amiloride (By similarity). Mediates the influx of adrenaline, noradrenaline (norepinephrine), dopamine, cimetidine, famotidine, metformin, N-1-methylnicotinamide (NMN), 1-methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), oxaliplatin and cisplatin. Cisplatin may develop a nephrotoxic action. Transport of creatinine is inhibited by fluoroquinolones such as DX-619 and LVFX. This transporter is a major determinant of the anticancer activity of oxaliplatin and may contribute to antitumor specificity.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:SLC22A2

Reactivity:Rat

Assay type:Sandwich

Sensitivity:8.85ng/L

Detection range:20-3800ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Solute carrier family 22 member 2

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9R0W2

MASS(Da):62,343

GeneID:29503

Synonyms:44471;OCT2r;Organic cation transporter 2;rOCT2;SLC22A2;Solute carrier family 22 member 2

Gene names:Slc22a2

Standard solution:4000ng/L