Rat Ryanodine receptor 1,RyR1 ELISA KIT

SKU: E3333Ra

Size:96 Tests-1 Kit

Background:Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules (PubMed:11316255). Repeated very high-level exercise increases the open probability of the channel and leads to Ca(2+) leaking into the cytoplasm (By similarity). Can also mediate the release of Ca(2+) from intracellular stores in neurons, and may thereby promote prolonged Ca(2+) signaling in the brain. Required for normal embryonic development of muscle fibers and skeletal muscle. Required for normal heart morphogenesis, skin development and ossification during embryogenesis (By similarity). {ECO:0000250|UniProtKB:E9PZQ0, ECO:0000250|UniProtKB:P11716, ECO:0000305|PubMed:11316255}.

Research_area:

Applications:ELISA

Target_protein:Ryr1

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.54ng/ml

Detection range:1-64ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:F1LMY4

MASS(Da):565483

GeneID:

Synonyms:Ryr1

Gene names:Ryr1

Standard solution:128ng/ml