Rat Rantes PicoKine® Quick ELISA Kit

SKU: FEK0496

Size: 96 wells/kit, with removable strips.

Storage: Store at 4°C for 6 months. (Ships with gel ice, can store for up to 3 days in room temperature. Refrigerate upon receipt.)

Form:

Reactivity: Rat

Applications: ELISA

Application Details:

Gene Name: CST3

Specificity: Natural and recombinant Rat Ccl5

Background: Rantes (regulated on activation normal T cell expressed and secreted) is one of the natural ligands for the chemokine receptor CCR5 and potently suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Peripheral blood mononuclear cells or CD4 (+) lymphocytes obtained from different individuals have wide variations in their ability to secrete RANTES. The Rantes gene product is predicted to be 10 kDa and, after cleavage of the signal peptide, approximately 8 kDa. Of the 68 residues, 4 are cysteines, and there are no sites for N-linked glycosylation. Rantes is expressed by cultured T cell lines that are Ag specific and growth factor dependent.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: S24-S91

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Reference:

Uniprot ID: P50231

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 81780

Protein Name: C-C motif chemokine 5

Gene Full Name: chemokine (C-C motif) ligand 5

Synonyms: C C motif chemokine 5; CCL5; chemokine (C C motif) ligand 5; D17S136E; EoCP; RANTES; SCYA5; SIS delta; SISd; Small inducible cytokine A5; T cell specific protein P228; T cell specific protein RANTES; TCP228