Rat Multidrug and Toxin Extrusion Protein 1, SLC47A1 ELISA Kit

SKU: E1814Ra

Size:96 Tests-1 Kit

Background:Solute transporter for tetraethylammonium (TEA), cimetidine, metformin, guanidine, N-methylnicotinamide (NMN) and also the zwitterionic cephalosporin cephalexin. Not a transporter for 1-methyl-4-phenylpyridinium (MPP), procainamide, creatinine, guanidine, p-aminohippurate (PAH) and the anionic cephalosporin cefalozin. MPP-transport activity has been observed in PubMed: 16928787 and PubMed: 17047166 and may contradict results observed in PubMed: 16850272. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Responsible for the secretion of cationic drugs across the brush border membranes.

Research_area:Others

Applications:ELISA

Target_protein:SLC47A1

Reactivity:Rat

Assay type:Sandwich

Sensitivity:5.33ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Multidrug and Toxin Extrusion Protein 1

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q5I0E9

MASS(Da):61,440

GeneID:360539

Synonyms:MATE-1;Multidrug and toxin extrusion protein 1;rMATE-1;SLC47A1;Solute carrier family 47 member 1

Gene names:SLC47A1

Standard solution:2400ng/L