Rat matrix metalloproteinase 24,MMP-24 ELISA KIT

SKU: E2530Ra

Size:96 Tests-1 Kit

Background:Metalloprotease that mediates cleavage of N-cadherin (CDH2) and acts as a regulator of neuro-immune interactions and neural stem cell quiescence. Involved in cell-cell interactions between nociceptive neurites and mast cells, possibly by mediating cleavage of CDH2, thereby acting as a mediator of peripheral thermal nociception and inflammatory hyperalgesia. Key regulator of neural stem cells quiescence by mediating cleavage of CDH2, affecting CDH2-mediated anchorage of neural stem cells to ependymocytes in the adult subependymal zone, leading to modulate their quiescence. May play a role in axonal growth. Able to activate progelatinase A. May also be a proteoglycanase involved in degradation of proteoglycans, such as dermatan sulfate and chondroitin sulfate proteoglycans. Cleaves partially fibronectin, but not collagen type I, nor laminin. {ECO:0000269|PubMed:16495457}.

Research_area:

Applications:ELISA

Target_protein:Mmp24

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.021ng/ml

Detection range:0.05-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:matrix metalloproteinase 24

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q99PW6

MASS(Da):70465

GeneID:83513

Synonyms:Mmp24 Mt5mmp

Gene names:Mmp24

Standard solution:24ng/ml