Rat Latent Transforming Growth Factor Beta Binding Protein 1, LTBP1 ELISA Kit

SKU: E0944Ra

Size:96 Tests-1 Kit

Background:Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space (PubMed: 7593177). Associates specifically via disulfide bonds with the Latency-associated Peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta (By similarity). Outcompeted by LRRC32/GARP for binding to LAP regulatory chain of TGF-beta (By similarity).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:LTBP1

Reactivity:Rat

Assay type:Sandwich

Sensitivity:9.14ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Latent Transforming Growth Factor Beta Binding Protein 1

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q00918

MASS(Da):186,599

GeneID:59107

Synonyms:Latent-transforming growth factor beta-binding protein 1;LTBP 1;LTBP1;LTBP-1;TGF-beta-1-BP-1;Transforming growth factor beta-1-binding protein 1;Transforming growth factor beta-1-masking protein large subunit

Gene names:LTBP1

Standard solution:4800ng/L