Rat Interleukin 11, IL-11 ELISA Kit

SKU: E0109Ra

Size:96 Tests-1 Kit

Background:Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and IL11RA activates a signaling cascade that promotes cell proliferation. Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. The interaction with the membrane-bound IL11RA and IL6ST stimulates 'classic signaling', whereas the binding of IL11 and soluble IL11RA to IL6ST stimulates 'trans-signaling'.

Research_area:Immunology

Applications:ELISA

Target_protein:IL-11

Reactivity:Rat

Assay type:Sandwich

Sensitivity:5.28ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Interleukin 11

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q99MF5

MASS(Da):21,555

GeneID:171040

Synonyms:IL 11;IL11;Il-11;Interleukin-11

Gene names:Il11

Standard solution:2400ng/L