Rat Gliomedin, GLDN ELISA Kit

SKU: E1980Ra

Size:96 Tests-1 Kit

Background:Ligand for NRCAM and NFASC/neurofascin that plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Mediates interaction between Schwann cell microvilli and axons via its interactions with NRCAM and NFASC (PubMed: 16039564). Nodes of Ranvier contain clustered sodium Channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium Channels at heminodes; not required for the formation of mature nodes with normal sodium Channel clusters. Required, together with NRCAM, for maintaining NFASC and sodium Channel clusters at mature nodes of Ranvier (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:GLDN

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.048ng/mL

Detection range:0.1-40ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Gliomedin

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q80WL1

MASS(Da):59330

GeneID:315675

Synonyms:GLDN;Gliomedin shedded ectodomain

Gene names:GLDN

Standard solution:48ng/mL